The CDB for FibromyalgiaMalik Qasir
Learning the use of cannabidiol (CBD)
Cannabidiol (CBD) is a chemical compound made from marijuana. CBD is not psychoactive, unlike tetrahydrocannabinol (THC), the other by-product of cannabis. CBD is thought to activate the receptors for serotonin. It has a role to play in:
- Perception of pain
- Maintaining temperature of the skin
- reducing inflammation
According to recent studies, the CBD has also:
- Helps to ease the symptoms of depression
- Possibly prevent symptoms of psychosis
Such effects make CBD an attractive alternative therapy for pain conditions such as fibromyalgia.
CBD studies on fibromyalgia
Fibromyalgia is a chronic pain disorder that causes musculoskeletal pain in addition to the following:
- Cognitive Disorders
It mostly affects women, and there is currently no known treatment for the disease. Nonetheless, treatment options that concentrate on pain management are available.
CBD has been used to reduce chronic symptoms of pain and inflammation. It is viewed as an alternative to the use of opioid prescriptions that can be addictive.
Nonetheless, the Food and Drug Administration (FDA) has not approved CBD as a treatment option for fibromyalgia or most other disorders. The CBD-based prescription drug Epidiolex, an epilepsy treatment, is the only CBD medication approved and supervised by the FDA.
Actually, there are no published studies on fibromyalgia that consider the impact of CBD on its own. Nonetheless, some work has looked at the effects of cannabis, which may contain multiple cannabinoids, on fibromyalgia. The findings were mixed. More human studies are needed here.
A 2009 reviewTrusted Source found that CBD may be used to alleviate neuropathic pain. Researchers concluded that cannabinoids such as CBD may be beneficial as an alternative to other pain medications.
A research in 2011 looked at 56 individuals with fibromyalgia. The bulk of the participants were female.
The research participants consisted of two groups:
- One group consisted of 28 study participants who were not cannabis users.
- The second group was made up of 28 study participants who were cannabis users. The rate of cannabis use or the amount of cannabis they used varied.
Two hours after marijuana was used, cannabis users had benefits such as:
- Decreased pain and stiffness
- Increased sleepiness
They also had a slightly higher score on mental health than non-users.
The Dutch study of 2019
A study in 2019 in the Netherlands looked at the effect of cannabis on 20 women with fibromyalgia. During the course of the study, each participant received four types of cannabis:
- An unspecified amount of placebo, which did not contain any CBD or THC
- 200 milligrams (mg) of a variety with high levels of CBD and THC (Bediol)
- 200 mg of a variety with high levels of CBD and low levels of THC (Bedrolite)
- 100 mg of a variety with low CBD levels and high THC levels (Bedrocan)
Researchers found that the spontaneous pain scores of people using placebo were similar to the spontaneous pain scores of people using some non-placebo varieties.
However, bediol, which is high in CBD and THC, has relieved more people than placebo. This resulted in a 30% reduction in spontaneous pain among 18 of the 20 participants. Placebo caused a 30% reduction in spontaneous pain in 11 participants.
Use of Bediol or Bedrocan, both high-THC varieties, significantly improved pressure pain thresholds compared to placebo.
Bedrolite, which is high in CBD and low in THC, showed no evidence of being able to relieve spontaneous or evoked pain.
Study in Israel in 2019
Hundreds of people with fibromyalgia are studied over a period of at least six months in an Israeli experiment in 2019. 82 percent of the participants were women. Nurses provided guidance to the study participants before taking medical cannabis. The nurses gave advice on:
- The 14 strains of cannabis available
- Method of delivery
All participants began with a low dose of cannabis, and over the course of the study, dosages were gradually increased. The approved median marijuana dosage began at 670 mg a day.
The licensed median marijuana dosage was 1,000 mg a day at 6 months of age. The approved median dose of THC was 140 mg, and the approved median dose of CBD was 39 mg per day.
The researchers recognized the weaknesses of the analysis. For example, only about 70 percent of participants were able to follow-up. It also made it difficult to compare the results of CBD-rich and THC-rich strains by using so many different strains.
They also concluded, however, that medical cannabis was a safe and effective fibromyalgia remedy.
52.5 percent of participants, or 193 individuals, identified their level of pain as high at the start of the study. Only 7.9% of those who responded, or 19 people, reported high levels of pain at the6-month follow-up.
Methods for CBD diagnosis
You will find CBD products that contain only trace amounts of THC if you want to prevent the psychoactive effects of marijuana. You can find CBD products that contain higher concentrations of THC if you live in a place where recreational or medical marijuana is legal.
While they each have separate benefits, when combined, CBD and TCH probably work best. Experts call this synergy, or interaction, the “entourage effect.” CBD also acts against THC-targeted receptors to reduce marijuana’s negative effects, such as paranoia and anxiety.
In a number of ways you can consume CBD, including:
- Smoking or vaporization. Smoking CBD-rich marijuana is the best way to reduce symptoms if you want to relieve immediate pain. Effects can last for up to three hours. You can directly inhale CBD from the cannabis plant by smoking or vaping, absorbing the chemical into your bloodstream and lungs.
- Edible. Edible. Edibles are foods that are cooked with the cannabis plant, or oil or butter infused with cannabis. Experiencing symptom relief can take longer, but edible results can last for up to 6 hours.
- Extracts of oil. Under the tongue, oils can be applied topically, taken orally or dissolved and absorbed in mouth tissues.
- Topicals. CBD oils can be infused into topical creams or balms and applied directly to the skin. These CBD products can be an effective way to reduce inflammation and help with external pain.
There may be respiratory risks associated with smoking or vaporizing marijuana. People with asthma or lung conditions should not use this method. You should also follow the dosage instructions carefully, especially with edibles, in order to avoid the negative side effects of taking too much.
Side effects of CBD
Cannabidiol is known to be healthy and to have minimal side effects. Nonetheless, many people have experienced the following side effects following the use of CBD:
- The Appetite Switch
- Changes in weight
Research on mice linked the intake of CBD to the toxicity of the liver. Nevertheless, some of the mice in that study were injected with a large amount of CBD in the form of a CBD-rich cannabis extract.
Drug interactions with CDB are likely. Keep them in mind if you are currently taking any other supplements or drugs.
CBD, like grapefruit, also interferes with cytochrome P450 (CYP). This group of enzymes is essential for drug metabolism.
Outlook of the
Scientists are still researching whether CBD can effectively treat chronic pain conditions. More studies are expected. There are some success stories, but CBD is not FDA-approved for fibromyalgia. Evidence is also yet to tell us the long-term effects of CBD on the body.
Modern fibromyalgia therapy is recommended until more is learned.
When you plan to use CBD products for pain management, make sure to consult a doctor first. These can help you avoid negative side effects or dangerous interactions with your current medications and treatments.
Is the CDB legal? Marijuana-derived CBD products remain illegal at the federal level, but are legal under some state laws. Hemp-derived CBD products (with less than 0.3 per cent THC) are legal at the federal level, but are still prohibited under some state legislation. Check the laws of your state and the laws of wherever you fly. Keep in mind that non-prescription CBD products are not FDA-approved and may be wrongly labeled.